Being overweight doubles IVF miscarriage risk
Published: 28th Jun 2010 14:49:42
Overweight women undergoing fertility treatment have double the risk of miscarriage of normal weight women, a UK study says.
More than a third of overweight and obese women had a miscarriage compared with one in five of normal weight women, a fertility conference heard.
Previous research has shown that women who conceive naturally are also at a higher risk if they are overweight.
Experts warned that obesity is putting women's fertility at risk.
The study in more than 300 women was carried out at the fertility clinic at Guy's and St Thomas' Hospital in London.
All the women had been implanted with a single five-day-old embryo that had been fertilised in the laboratory.
Half of them had a body mass index (BMI) of more than 25, which is classed as overweight. Fourteen per cent had a BMI of 30 or more, which is classed as clinically obese.
The advice should be the same for any woman - that it is important to lose weight independent of how you conceive
The researchers said there was no difference in egg or embryo quality at the start of the procedure, the European Society of Human Reproduction and Embryology conference heard.
Yet in women with a BMI of over 25 there was a 35% miscarriage rate.
This compared with 21% in women with a BMI less than 25.
After taking into account factors that may influence the risk of miscarriage, such as age, and smoking history, they found the risk of miscarriage was double in the overweight group.
It is not known exactly why carrying extra weight increases the risk of miscarriage.
But one theory is that it may affect the lining of the womb and the success of implantation of the egg.
It is known that obesity is linked with increased health risks throughout pregnancy including pre-eclampsia and premature delivery.
Study leader Dr Tarek El-Toukhy said women undergoing IVF should be advised of the risks if they are overweight.
But he added: "The advice should be the same for any woman - that it is important to lose weight independent of how you conceive."
Professor Adam Balen, who works in Leeds and who wrote the British Fertility Society Guidelines on IVF in obese women, said 30 to 35% of women of reproductive age have a BMI over 30, putting their fertility in jeopardy.
He said that fertility clinics had to balance supporting women to lose weight with the knowledge that their age is often against them and fertility treatment should be started as soon as possible.
And he added: "There is an important health message here and new guidance has said that overweight women should take a higher dose of folic acid because of evidence their babies have a higher risk of congenital abnormalities."
Mr Tony Rutherford, chairman of the British Fertility Society, said all women should be advised to achieve a weight appropriate to their height before embarking on infertility treatment.
"We would like to see further resources put towards supporting women to lose weight to improve their chances of conceiving and maintaining a healthy pregnancy."
At 05:28:48 in EnglandThe Conservatives have said they will not subsidise new onshore wind farms if they win the 2015 general election.
At 04:37:25 in EnglandA man impaled in the neck by an industrial drill in a "freak accident" has been taken to hospital.
At 04:26:59 in HealthThe number of older people in England needing care will "outstrip" the number of family members able to provide it by 2017, a think tank has warned.
At 04:21:05 in HeadlinesUS President Barack Obama is meeting Japanese Prime Minister Shinzo Abe for talks on regional security and trade, on the first full day of his Asia tour.
At 04:02:52 in HeadlinesThe UN Secretary General has accused all parties in Syria's civil war of "flagrant violations" of international law over the delivery of aid.
At 04:00:21 in HeadlinesCanada says it will phase out the type of rail tankers involved in a deadly train derailment last July.
At 03:49:53 in HeadlinesThe oldest former player with Major League Baseball, Conrado "Connie" Marrero, has died in at home in Havana at the age of 102.
At 03:28:13 in WorldIndians are voting in the sixth phase of a marathon general election in which the governing Congress party is fighting the main opposition BJP.
At 03:13:22 in ScotlandThe last avalanche forecast of the latest Sportscotland Avalanche Information Service (SAIS) season has been published.
At 03:06:05 in ScotlandWhen Nicola Sturgeon joined the SNP, pursuing a career in politics was not her agenda.
Harvard CitationBBC News, 2010. Being overweight doubles IVF miscarriage risk [Online] (Updated 28th Jun 2010)
Available at: http://www.ukwirednews.com/news/70925/Being-overweight-doubles-IVF-miscarriage-risk [Accessed 24th Apr 2014]
News In Other Categories
Cult comic character Frank Sidebottom has inspired a film starring Michael Fassbender, while a documentary and biography are also in the works. Four years after his creator Chris Sievey died, why is Frank's legend growing and who was the man behind the mask?
The number of older people in England needing care will "outstrip" the number of family members able to provide it by 2017, a think tank has warned.
Shares in Qualcomm, one of the world's biggest chipmakers, fell 5% in after hours trading as it issued a weaker than expected growth outlook.
The Irish education minister has proposed a radical shake-up of the further education sector.
With the doors to its brand new £1million training centre officially open, one of the UK's leading apprentice training providers, Bristol based S&B Automotive Academy, is showcasing its world-class facilities by launching a series of foreign student exchanges for the first time in its 41-year history. To get a flavour of what life is like as an apprentice in the UK, the Academy hosted 16 apprentice engineers and bus drivers from the G9 Automotive College in Hamburg, Germany, as part of a Europe-wide vocational training initiative called the ‘Leonardo Programme’ with support from the European Social Fund. In a reciprocal arrangement, S&B will be sending nine apprentices to Germany during February 2012 so that they can get an appreciation of life in the automotive industry on the Continent. A further three German exchange groups are being planned for next year. Designed to assist the development of vocational skills and training across Europe, including work placements for trainees, the Leonardo Programme has a budget of €1.75bn, which is helping to encourage UK organisations to work with their counterparts abroad. In what is expected to be another challenging year for employers in the UK automotive sector, S&B’s Chief Executive, Jon Winter, claims that the exchange initiative will bring many benefits to the Academy and its apprentices: “In a world of global automotive brands, it’s important for our learners to understand the international context of the industry they have chosen to make their career. This new exchange programme will enable apprentices and Academy staff alike to achieve a better understanding of the challenges and opportunities within the automotive arena in Europe. With the Academy’s influence also extending to the USA and Asia, there’s every possibility that this initiative could move further afield in the future.” Continued Winter: “The need for skilled technicians across the world is on the increase and we actively encourage our apprentices to look at broader horizons during their training. Many of them have already learned the phrase ‘Vorsprung durch Gelehrtheit’, quite simply, ‘Advancement through learning.” In the 2010/11 academic year, S&B doubled the number of successful Apprenticeships over the previous year with some 350 apprentices graduating from the Academy. At the same time, achievement levels reached an all-time high with an overall success rate of 85%. For those learners on the Advanced Apprenticeship three-year programme, success rates were even higher, at over 98%. PHOTO CAPTION: As part of their exchange visit, S&B Automotive Academy arranged for the German apprentices to visit Hampshire bus operator, Bluestar, at its Barton Park depot. The students are pictured with S&B’s Andy West (3rd right) and Steve Prewett, Bluestar’s Area Engineering Manager (2nd right). Ends http://www.sandbaa.com